Surwit模型饲料介绍
Surwit Diet
formulas
脂肪58%，糖约25%，饲料热量大约是5.5千卡/g
【2】Surwit 58%高脂低糖饲料：脂肪约58%。饲料热量大约是5.5千卡/g。
【3】Surwit 11%低脂高糖饲料：脂肪热量11%，糖61%。
【4】Surwit 11%低脂低糖饲料：脂肪热量11%。
Surwit等在研究高脂肥胖及其并发症方面，可谓是元老级和权威学者，他们的两个关键性研究所用的模型饲料至今被广为采用，并且后来有些学者和有些实验动物饲料企业在此基础上设计出了其他模型饲料。
一、Surwit diet介绍
Surwit等研究者在80年代已经设计了高脂高糖饲料用于研究饮食所致肥胖和糖尿病的研究。所用的模型饲料就是右图中所列的58%高脂高糖饲料。下图是用Surwit的这种模型饲料喂养的效果比较。
随着他们继续深入研究，到了90年代，他们又进一步观察比较了高脂高糖和高脂低糖分别对体重（肥胖）的作用，糖与脂肪之间对体脂的相互作用。为了达到研究目的，他们设计了2种高脂饲料，即高脂高糖饲料和高脂低糖饲料，以及2种低脂饲料，即低脂高糖饲料和低脂低糖饲料，从而形成了2个水平的脂肪含量（高脂、低脂）、2个水平的糖含量（高糖、低糖）的4种组合，也就是4种饲料。
他们获得的关键性发现是，高脂高糖饲料和高脂低糖都能让动物肥胖，但是，高脂高糖饲料比高脂低糖饲料的肥胖程度更大，更重要的是，高脂高糖和高脂无糖虽然都能升高血糖和空腹胰岛素水平，但是，两者之间并没有差别，也就是，高脂情况下，糖含量高低对于血糖和空腹胰岛素水平没有起作用。
那么，两种高脂饲料喂养的动物之间，为什么高脂高糖饲料引起的肥胖程度更大？关键是动物对高脂高糖饲料的食物利用率（FE）增大。更有趣的是，在体重和体脂两项指标方面，他们发现低脂高糖喂养的动物比低脂低糖的动物明显降低（变瘦）。呵呵，“减肥”？确实，后来Surwit等研究者又进一步在人体研究了低脂高糖的减体重的效果。
Surwit等研究者在这些研究中所用的4种饲料后来被称为，称为Surwit diet。
由于第4种饲料是低脂对照饲料，因此，前3种被后来作为模型饲料。
Surwit模型饲料的用途即为广泛，见右图。
如今广为采用的van Heek系列的45%高脂肥胖模型饲料和60%高脂肥胖模型饲料就是基于Surwit模型饲料基础上延伸而来。
二、Surwit diet应用的注意点
Surwit模型也存在缺点：营养素不合理，需要优化。
南通特洛菲饲料科技有限公司对4种模型饲料分别采取了优化（产品代码TP24200）和不优化（产品代码TP24220）的策略，甚至重新设计（产品代码TP24000和TP24100）。
如果读者准备使用Surwit饲料开展研究，请阅读“Surwit高脂高糖和高脂低糖模型饲料存在的问题与纠正”。
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南通特洛菲饲料科技有限公司提供各种动物、各种类型的肥胖及其并发症的模型饲料。以下介绍Surwit模型饲料。
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大鼠小鼠Surwit模型饲料：
TP24220, TP24221
TP24220和TP24221分别与Surwit高脂高糖模型饲料、高脂低糖模型饲料一致，与ResearchDiets公司D12331和D12330相当，或者与TestDiet公司58R3和58R2相当。为追求与Surwit饲料相当的研究者设计。用于未成年（接近成年），建议不用于幼年、妊娠哺乳期。
TP24200
由于Surwit模型饲料营养素不合理，TP24200将营养素优化到合理水平。用于未成年，建议不用于幼年、妊娠、哺乳期。
TP24100
基于Surwit模型饲料重新设计，用于成年动物。
TP24000
基于Surwit模型饲料重新设计，适用于未成年（任何阶段）、妊娠、哺乳期。