Hayek（TD88137）西方饮食模型饲料介绍
Hayek Diet（TD88137）for Western Diet Model
一、Hayek模型饲料
Hayek等早在90年代早期研究时进行人类脂蛋白转基因鼠的研究，所设计的西方饮食模型饲料主要是脂肪21.2%，碳水化合物49.1%，蛋白质19.8%，胆固醇0.2%。这个模型饲料的特点是脂肪全部是奶油，虽然也是高胆固醇，但是胆固醇含量只有0.2%，不像Paigen饲料中用到1.25%，而且其中不添加胆盐。所采用的这个模型饲料在Harlan（Teklad）公司生产，编号为TD88137。
很显然，基于对这个模型饲料的最大贡献，应该叫做Hayek模型饲料，但是，文献中都叫做TD88137。
与ResearchDiets公司相比，Harlan公司的做法有些欠妥。ResearchDiet公司在与van Heek等研究者合作时诞生的45%高脂肥胖饲料（D12451），后来又在此基础上制作的60%高脂肥胖饲料（D12492）都是以van Heek来称呼的，叫做van Heek系列模型饲料，这显然是肯定了van Heek的贡献。然而，Harlan公司与Hayek等研究者合作的西方饮食模型饲料（TD88137），在介绍TD88137时只是说他们公司与某某某大学的研究者们合作，没有具体说明哪些研究者。这也许是至今很少有论文中提及Haylek（甚至很多研究中没有引用Haylek等的研究论文）的原因。
二、Hayek模型饲料的用途和缺点
Hayek模型饲料已经在大鼠和小鼠等不同动物中使用，广泛应用于多种西方饮食疾病的研究，见右图。
当今很多著名实验动物饲料企业都生产Hayek模型饲料。除了Harlan(Teklad)公司生产的TD88137，其他公司的情况是：ResearchDiets是D12079B。
在国内，特洛菲饲料科技有限公司采取了优化（TP26301, TP26302）、不优化（TP26300）和重新设计（TP26302和TP26304）三种策略提供不同的高脂肥胖模型饲料供研究者选用，并且提供了各种匹配的对照饲料供研究者根据研究的具体情况选择。
如果读者准备使用Hayek饲料开展研究，请阅读“Hayek（TD88137）西方饮食模型饲料存在的问题和纠正”。
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南通特洛菲饲料科技有限公司提供各种动物、各种类型的肥胖及其并发症的模型饲料。以下介绍与TD88137相当或者优化、重新设计的西方饮食模型饲料。
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大鼠小鼠西方饮食模型饲料：
TP26300
与Harlan公司TD88137相当。为追求与原作者使用的TD88137的研究者设计。用于未成年。
TP26301
由于TD88137的必需脂肪酸过少, TP26301进行了优化，与ResearchDiets公司D12079B相当。用于未成年。
TP26302
TD88137的营养素不科学、不合理, TP26302进行了优化。用于未成年期。
TP26303
TP26303针对TD88137进行了全面优化，用于未成年期。
TP26304
由于TD88137不适合成年期喂养, TP26304在TD88137基础上专为成年期设计。营养素符合成年期要求。
TP26305
TP26305专为成年期设计，避免必需脂肪酸过低，又营养素合理。
详细情况，请浏览：Hayek西方饮食模型饲料(Hayek Western-type Diet)选择指南